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Evaluation of a protocol-based intervention to promote timely switching from intravenous to oral paracetamol for post-operative pain management: an interrupted time series analysis
journal contribution
posted on 2023-06-09, 15:05 authored by Nirmeen Sabry, Dalia Dawoud, Adel Alansary, Natalia HounsomeNatalia Hounsome, Darrin BainesRationale, aims and objectives Timely switching from intravenous to oral therapy ensures optimized treatment and efficient use of health care resources. Intravenous (IV) paracetamol is widely used for post-operative pain management but not always switched to the oral form in a timely manner, leading to unnecessary increase in expenditure. This study aims to evaluate the impact of a multifaceted intervention to promote timely switching from the IV to oral form in the post-operative setting. Methods An evidence-based prescribing protocol was designed and implemented by the clinical pharmacy team in a single district general hospital in Egypt. The protocol specified the criteria for appropriate prescribing of IV paracetamol. Doctors were provided with information and educational sessions prior to implementation. A prospective, quasi-experimental study was undertaken to evaluate its impact on IV paracetamol utilization and costs. Data on monthly utilization and costs were recorded for 12 months before and after implementation (January 2012 to December 2013). Data were analysed using interrupted time series analysis. Results Prior to implementation, in 2012, total spending on IV paracetamol was 674?154.00 Egyptian Pounds (L.E.) ($23?668.00). There was a non-significant (P?>?0.05) downward trend in utilization (-32 ampoules per month) and costs [reduction of 632?L.E. ($222) per month]. Following implementation, immediate decrease in utilization and costs (P?
History
Publication status
- Published
Journal
Journal of Evaluation in Clinical PracticeISSN
1356-1294Publisher
WileyExternal DOI
Issue
6Volume
21Page range
1081-1088Department affiliated with
- Global Health and Infection Publications
Research groups affiliated with
- Wellcome Trust Brighton and Sussex Centre for Global Health Research Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2018-09-14First Compliant Deposit (FCD) Date
2018-09-13Usage metrics
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