Leach, M. O., Brindle, K. M., Evelhoch, J. L., Griffiths, J. R., Horsman, M. R., Jackson, A., Jayson, G. C., Judson, I. R., Knopp, M. V., Maxwell, R. J., McIntyre, D., Padhani, A. R., Price, P., Rathbone, R., Rustin, G. J., Tofts, P. S., Tozer, G. M., Vennart, W., Waterton, J. C., Williams, S. R. and Workman, P. (2005) The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. British Journal of Cancer, 92 (9). pp. 1599-610. ISSN 0007-0920

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Abstract

Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.

Item Type:	Article
Keywords:	Angiogenesis Inhibitors/ therapeutic use Antineoplastic Agents/ therapeutic use Clinical Trials Evaluation Studies Magnetic Resonance Imaging Neoplasms/ blood supply/ drug therapy Reproducibility of Results Terminology
Schools and Departments:	Brighton and Sussex Medical School > Brighton and Sussex Medical School
Depositing User:	Paul Stephen Tofts
Date Deposited:	28 Feb 2007
Last Modified:	11 Jun 2012 12:37
URI:	http://srodev.sussex.ac.uk/id/eprint/807
Google Scholar:	234 Citations

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