Freedom of movement

Rass, Ulrich (2019) Freedom of movement. Nature Chemical Biology. ISSN 1552-4450

[img] PDF - Accepted Version
Restricted to SRO admin only until 21 July 2019.

Download (50kB)


Holliday junction resolvases lock dynamic DNA four-way junctions into specific structural conformations for symmetric DNA cleavage. Single-molecule studies now reveal that resolvases can relax their grip, enabling Holliday junction conformer transitions and branch migration in the enzyme-bound form.

Item Type: Article
Keywords: Holliday junction resovases, homologous recombination
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Research Centres and Groups: Genome Damage and Stability Centre
Subjects: Q Science > Q Science (General)
Depositing User: Ulrich Rass
Date Deposited: 22 Jan 2019 10:24
Last Modified: 22 Jan 2019 11:17

View download statistics for this item

📧 Request an update