A

Adalat, Rooma, Saleem, Faiza, Crickmore, Neil, Naz, Shagufta and Shakoori, Abdul Rauf (2017) In vivo crystallization of three-domain cry toxins. Toxins, 9 (3). a80. ISSN 2072-6651

Adang, Michael J, Crickmore, Neil and Jurat-Fuentes, Jual Luis (2014) Diversity of bacillus thuringiensis crystal toxins and mechanism of action. In: Dhadialla, Tarlochan and Gill, Sarjeet (eds.) Insect Midgut and Insecticidal Proteins. Advances in Insect Physiology, 47 . Academic Press, pp. 39-87.

B

Berry, Colin and Crickmore, Neil (2017) Structural classification of insecticidal proteins – towards an in silico characterization of novel toxins. Journal of Invertebrate Pathology, 142. pp. 16-22. ISSN 0022-2011

Bi, Yang, Zhang, Yanrui, Shu, Changlong, Crickmore, Neil, Wang, Qinglei, Du, Lixin, Song, Fuping and Zhang, Jie (2014) Genomic sequencing identifies novel Bacillus thuringiensis Vip1/Vip2 binary and Cry8 toxins that have high toxicity to Scarabaeoidea larvae. Applied Microbiology and Biotechnology. ISSN 0175-7598

Biggart, Rachael, Caserta, Stefano and Llewelyn, Martin (2015) Investigating genetic polymorphisms in relation to asymptomatic Clostridium difficile infection. In: 4th European Congress of Immunology - Vienna 2015, 6-9 September 2015, Vienna, Austria.

Botella, Hélène, Peyron, Pascale, Levillain, Florence, Poincloux, Renaud, Poquet, Yannick, Brandli, Irène, Wang, Chuan, Tailleux, Ludovic, Tilleul, Sylvain, Charrière, Guillaume M, Waddell, Simon J, Foti, Maria, Lugo-Villarino, Geanncarlo, Gao, Qian, Maridonneau-Parini, Isabelle, Butcher, Philip D, Castagnoli, Paola Ricciardi, Gicquel, Brigitte, de Chastellier, Chantal and Neyrolles, Olivier (2011) Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages. Cell Host and Microbe, 10 (3). pp. 248-259. ISSN 1931-3128

C

Castañeda-García, A, Prieto, A I, Rodríguez-Beltrán, J, Alonso, N, Cantillon, D, Costas, C, Pérez-Lago, L, Zegeye, E D, Herranz, M, Plociński, P, Tonjum, T, García de Viedma, D, Paget, M, Waddell, S J, Rojas, A M, Doherty, A J and Blázquez, J (2017) A non-canonical mismatch repair pathway in prokaryotes. Nature Communications, 8. a14246. ISSN 2041-1723

D

De Seabra Rodrigues Dias, Ivo Ricardo (2012) Effects of virulence and fraction 1 antigens from Yersinia pestis on the human innate immune system. Doctoral thesis (PhD), University of Sussex.

E

Erskine, Elliot, Morris, Ryan J, Schor, Marieke, Earl, Chris, Gillespie, Rachel M C, Bromley, Keith, Sukhodub, Tetyana, Clark, Lauren, Fyfe, Paul, Serpell, Louise C, Stanley-Wall, Nicola R and MacPhee, Cait E (2018) Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA. Molecular Microbiology. ISSN 0950-382X

Evangelopoulos, Dimitrios, Fonseca, Joana Diniz da and Waddell, Simon J (2015) Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model them. International Journal of Infectious Diseases, 32. pp. 76-80. ISSN 1201-9712

Evangelopoulos, Dimitrios and Waddell, Simon (2016) The use of transcriptomics to predict drug efficacy and treatment outcome in tuberculosis. In: Kurosu, Michio and Denny, William (eds.) Advances in Tuberculosis Medicinal Chemistry. Future Science Ltd, pp. 90-103. ISBN 9781910419144

F

Feeney, Morgan A, Chandra, Govind, Findlay, Kim C, Paget, Mark S B and Buttner, Mark J (2017) Translational control of the SigR-directed oxidative stress response in streptomyces via IF3-mediated repression of a noncanonical GTC start codon. mBio, 8 (3). e00815-17. ISSN 2150-7511

G

Gilks, William (2016) Read-mapping for next-generation sequencing data (Wolbachia). [Dataset]

H

Hemingway, Cheryl, Berk, Maurice, Anderson, Suzanne T, Wright, Victoria J, Hamilton, Shea, Eleftherohorinou, Hariklia, Kaforou, Myrsini, Goldgof, Greg M, Hickman, Katy, Kampmann, Beate, Schoeman, Johan, Eley, Brian, Beatty, David, Pienaar, Sandra, Nicol, Mark P, Griffiths, Michael J, Waddell, Simon J, Newton, Sandra M, Coin, Lachlan J, Relman, David A, Montana, Giovanni and Levin, Michael (2017) Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function. PLoS ONE, 12 (11). e0185973. ISSN 1932-6203

Hernández-Martínez, Patricia, Hernández-Rodríguez, Carmen Sara, Krishnan, Vidisha, Crickmore, Neil, Escriche, Baltasar and Ferré, Juan (2012) Lack of Cry1Fa binding to the midgut brush border membrane in a resistant colony of Plutella xylostella moths with a mutation in the ABCC2 locus. Applied and Environmental Microbiology, 78 (18). pp. 6759-6761. ISSN 0099-2240

Honeyborne, Isobella, McHugh, Timothy D, Kuittinen, Iitu, Cichonska, Anna, Evangelopoulos, Dimitrios, Ronacher, Katharina, van Helden, Paul D, Gillespie, Stephen H, Fernandez-Reyes, Delmiro, Walzl, Gerhard, Rousu, Juho, Butcher, Philip D and Waddell, Simon J (2016) Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy. BMC Medicine, 14 (68). ISSN 1741-7015

Hubin, Elizabeth A, Tabib-Salazar, Aline, Humphrey, Laurence J, Flack, Joshua E, Olinares, Paul Dominic B, Darst, Seth A, Campbell, Elizabeth A and Paget, Mark S (2015) Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA. Proceedings of the National Academy of Sciences, 112 (23). pp. 7171-7176. ISSN 1091-6490

Humphrey, Laurence J (2016) Transcription initiation in Streptomyces coelicolor A3(2). Doctoral thesis (PhD), University of Sussex.

J

Jagatia, Heena (2018) The biological role and mechanism of action of rbpA and carD in Streptomyces coelicolor A3 (2) and Mycobacterium tuberculosis. Doctoral thesis (PhD), University of Sussex.

Jurat-Fuentes, Juan Luis and Crickmore, Neil (2017) Specificity determinants for Cry insecticidal proteins: insights from their mode of action. Journal of Invertebrate Pathology, 142. pp. 5-10. ISSN 0022-2011

K

Kampmann, Beate, Hemingway, Cheryl, Stephens, Alick, Davidson, Robert, Goodsall, Anna, Anderson, Suzanne, Nicol, Mark, Schölvinck, Elisabeth, Relman, David, Waddell, Simon J, Langford, Paul, Sheehan, Brian, Semple, Lynn, Wilkinson, Katalin A, Wilkinson, Robert J, Ress, Stanley, Hibberd, Martin and Levin, Michael (2005) Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ. Journal of Clinical Investigation, 115 (9). pp. 2480-2488. ISSN 0021-9738

Krishnan, Vidisha, Domanska, Barbara, Elhigazi, Alicia, Afolabi, Fatai, West, Michelle J and Crickmore, Neil (2017) The human cancer cell active toxin Cry41Aa from Bacillus thuringiensis acts like its insecticidal counterparts. Biochemical Journal, 474 (10). pp. 1591-1602. ISSN 0264-6021

L

Li, Alice H, Waddell, Simon J, Hinds, Jason, Malloff, Chad A, Bains, Manjeet, Hancock, Robert E, Lam, Wan L, Butcher, Philip D and Stokes, Richard W (2010) Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages. PLoS ONE, 5 (6). e11066. ISSN 1932-6203

Li, Ming-Shi, Monahan, Irene M, Waddell, Simon J., Mangan, Joseph A, Martin, Steve L, Everett, Martin J and Butcher, Philip D (2001) cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG. Microbiology, 147 (8). pp. 2293-2305. ISSN 1350-0872

Li, Ming-Shi, Waddell, Simon, Monahan, Irene M, Mangan, Joseph A, Martin, Steve L, Everett, Martin J and Butcher, Philip D (2004) Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters. FEMS Microbiology Letters, 233 (2). pp. 333-339. ISSN 0378-1097

Li, Ying, Shu, Changlong, Zhang, Xuewen, Crickmore, Neil, Liang, Gemei, Jiang, Xingfu, Liu, Rongmei, Song, Fuping and Zhang, Jie (2014) Mining rare and ubiquitous toxin genes from a large collection of Bacillus thuringiensis strains. Journal of Invertebrate Pathology, 122C. pp. 6-9. ISSN 0022-2011

M

Makarov, Vadim, Manina, Giulia, Mikusova, Katarina, Möllmann, Ute, Ryabova, Olga, Saint-Joanis, Brigitte, Dhar, Neeraj, Pasca, Maria Rosalia, Buroni, Silvia, Lucarelli, Anna Paola, Milano, Anna, De Rossi, Edda, Belanova, Martina, Bobovska, Adela, Dianiskova, Petronela, Kordulakova, Jana, Sala, Claudia, Fullam, Elizabeth, Schneider, Patricia, McKinney, John D, Brodin, Priscille, Christophe, Thierry, Waddell, Simon, Butcher, Philip, Albrethsen, Jakob, Rosenkrands, Ida, Brosch, Roland, Nandi, Vrinda, Bharath, Sowmya, Gaonkar, Sheshagiri, Shandil, Radha K, Balasubramanian, Venkataraman, Balganesh, Tanjore, Tyagi, Sandeep, Grosset, Jacques, Riccardi, Giovanna and Cole, Stewart T (2009) Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. Science, 324 (5928). pp. 801-804. ISSN 0036-8075

McGregor, Simon, Vasas, Vera, Husbands, Phil and Fernando, Chrisantha (2012) Evolution of associative learning in chemical networks. PLoS Computational Biology, 8 (11). e1002739. ISSN 1553-734X

Minas, Christopher, Waddell, Simon J and Montana, Giovanni (2011) Distance-based differential analysis of gene curves. Bioinformatics, 27 (22). pp. 3135-3141. ISSN 1367-4803

P

Perrone, Filomena, De Siena, Barbara, Muscariello, Lidia, Kendall, Sharon L, Waddell, Simon J and Sacco, Margherita (2017) A novel TetR-like transcriptional regulator is induced in acid-nitrosative stress and controls expression of an efflux pump in mycobacteria. Frontiers in Microbiology, 8 (2039). ISSN 1664-302X

R

Raymond, Ben, Wright, Denis J, Crickmore, Neil and Bonsall, Michael B (2013) The impact of strain diversity and mixed infections on the evolution of resistance to Bacillus thuringiensis. Proceedings of the Royal Society B: Biological Sciences, 280 (1769). p. 20131497. ISSN 0962-8452

Ruan, Lifang, Crickmore, Neil, Peng, Donghai and Sun, Ming (2015) Are nematodes a missing link in the confounded ecology of the entomopathogen Bacillus thuringiensis? Trends in Microbiology, 23 (6). pp. 341-346. ISSN 0966-842X

Ruan, Lifang, Crickmore, Neil and Sun, Ming (2015) Is there sufficient evidence to consider Bacillus thuringiensis a multihost pathogen? Response to Loguercio and Argôlo-Filho. Trends in Microbiology, 23 (10). p. 587. ISSN 0966-842X

Rycroft, Julian A, Gollan, Bridget, Grabe, Grzegorz J, Hall, Alexander, Cheverton, Angela M, Larrouy-Maumus, Gerald, Hare, Stephen A and Helaine, Sophie (2018) Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection. Nature Communications, 9 (1993). pp. 1-11. ISSN 2041-1723

S

Salina, Elena G, Waddell, Simon J, Hoffmann, Nadine, Rosenkrands, Ida, Butcher, Philip D and Kaprelyants, Arseny S (2014) Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states. The Open Biology Journal, 4 (10). ISSN 1874-1967

Shan, Yueming, Shu, Changlong, Crickmore, Neil, Liu, Chunqin, Xiang, Wensheng, Song, Fuping and Zhang, Jie (2014) Cultivable gut bacteria of scarabs (Coleoptera: Scarabaeidae) inhibit Bacillus thuringiensis multiplication. Environmental Entomology, 43 (3). pp. 612-6. ISSN 1938-2936

Shu, Changlong, Zhang, Fengjiao, Chen, Guihua, Joseph, Lazarus, Barqawi, Amina, Evans, Jacob, Song, Fuping, Li, Guoxun, Zhang, Jie and Crickmore, Neil (2017) A natural hybrid of a Bacillus thuringiensis Cry2A toxin implicates Domain I in specificity determination. Journal of Invertebrate Pathology, 150. pp. 35-40. ISSN 0022-2011

Shu, Changlong, Zhang, Jingtao, Chen, Guihua, Liang, Gemei, He, Kanglai, Crickmore, Neil, Huang, Dafang, Zhang, Jie and Song, Fuping (2013) Use of a pooled clone method to isolate a novel Bacillus thuringiensis Cry2A toxin with activity against Ostrinia furnacalis. Journal of Invertebrate Pathology, 114 (1). pp. 31-33. ISSN 0022-2011

Shu, Changlong, Zhou, Jianqiao, Crickmore, Neil, Li, Xianchun, Song, Fuping, Liang, Gemei, He, Kanglai, Huang, Dafang and Zhang, Jie (2016) In vitro template-change PCR to create single crossover libraries: a case study with B. thuringiensis Cry2A toxins. Scientific Reports, 6. p. 23536. ISSN 2045-2322

Sidders, Ben, Withers, Mike, Kendall, Sharon L, Bacon, Joanna, Waddell, Simon J, Hinds, Jason, Golby, Paul, Movahedzadeh, Farahnaz, Cox, Robert A, Frita, Rosangela, Ten Bokum, Annemieke M C, Wernisch, Lorenz and Stoker, Neil G (2007) Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biology, 8 (12). R265. ISSN 1465-6906

Sohail, Asma, Kanwal, Nazia, Ali, Muhammad, Sadia, Sobia, Masood, Ahmed Ijaz, Ali, Faheem, Iqbal, Furhan, Crickmore, Neil, Shaikh, Rehan Sadiq and Sayyed, Ali H (2012) Effects of glutathione-S-transferase polymorphisms on the risk of breast cancer: a population-based case-control study in Pakistan. Environmental Toxicology and Pharmacology, 35 (2). pp. 143-153. ISSN 1382-6689

Stokes, Richard W and Waddell, Simon J (2009) Adjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle. Future Microbiology, 4 (10). pp. 1317-1335. ISSN 1746-0921

T

Treanor, David (2018) Symbionts in societies: the biology of Wolbachia in social insects. Doctoral thesis (PhD), University of Sussex.

Turapov, Obolbek, Waddell, Simon J, Burke, Bernard, Glenn, Sarah, Sarybaeva, Asel A, Tudo, Griselda, Labesse, Gilles, Young, Danielle I, Young, Michael, Andrew, Peter W, Butcher, Philip D, Cohen-Gonsaud, Martin and Mukamolova, Galina V (2014) Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions. Antimicrobial Agents and Chemotherapy, 58 (5). pp. 2798-2806. ISSN 1098-6596

Turapov, Obolbek, Waddell, Simon J, Burke, Bernard, Glenn, Sarah, Sarybaeva, Asel A, Tudo, Griselda, Labesse, Gilles, Young, Danielle I, Young, Michael, Andrew, Peter W, Butcher, Philip D, Cohen-Gonsaud, Martin and Mukamolova, Galina V (2014) Oleoyl-coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria. Journal of biological chemistry, 289 (36). pp. 25241-25249. ISSN 1083-351X

W

Waddell, S J and Butcher, P D (2007) Microarray analysis of whole genome expression of intracellular Mycobacterium tuberculosis. Current Molecular Medicine, 7 (3). pp. 287-296. ISSN 1566-5240

Waddell, S J, Chung, G A, Gibson, K J C, Everett, M J, Minnikin, D E, Besra, G S and Butcher, P D (2005) Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv. Letters in applied microbiology, 40 (3). pp. 201-6. ISSN 0266-8254

Waddell, Simon, Garton, Natalie J, Sherratt, Anna L, Lee, Su-Min, Smith, Rebecca J, Senner, Claire, Hinds, Jason, Rajakumar, Kumar, Adegbola, Richard A, Besra, Gurdyal S, Butcher, Philip D and Barer, Michael R (2008) Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS Medicine, 5 (4). pp. 634-645. ISSN 1549-1676

Waddell, Simon J and Butcher, Philip D (2009) Intracellular microbe whole-genome expression profiling: methodological considerations and biological inferences. In: Ulrich, E Schaible and Haas, Albert (eds.) Intracellular Niches of Microbes– A Pathogen's Guide through the Host Cell. Wiley-VCH Publishers. ISBN 9783527322077

Waddell, Simon J and Butcher, Philip D (2013) Transcriptomic approaches to mapping responses to drug therapy for tuberculosis. In: MuHugh, Timothy D (ed.) Tuberculosis: laboratory diagnosis and treatment strategies. Advances in molecular and cellular microbiology series (21). CAB International, Wallingford, pp. 173-183. ISBN 9781845938079

Waddell, Simon J and Butcher, Philip D (2010) Use of DNA arrays to study transcriptional responses to antimycobacterial compounds. In: Methods molecular biology: antibiotic resistance protocols. Springer, pp. 75-91.

Waddell, Simon J, Butcher, Philip D and Stoker, Neil G (2007) RNA profiling in host-pathogen interactions. Current Opinion in Microbiology, 10 (3). pp. 297-302. ISSN 1369-5274

Waddell, Simon J, Hinds, Jason and Butcher, Philip D (2008) Whole genome analysis using microarrays. In: Parish, Tanya and Brown, Amanda Claire (eds.) Mycobacteria Protocols : Second Edition. Methods in Molecular Biology, 465 . Springler, Totowa, NJ, pp. 1-12. ISBN 978-1-58829-889-8

Waddell, Simon J, Laing, Ken, Senner, Claire and Butcher, Philip D (2008) Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies. BMC Genomics, 9. p. 94. ISSN 1471-2164

Waddell, Simon J, Stabler, Richard A, Laing, Ken, Kremer, Laurent, Reynolds, Robert C and Besra, Gurdyal S (2004) The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds. Tuberculosis, 84 (3-4). pp. 263-274. ISSN 1472-9792

Waddell, Simon J, Tailleux, Ludovic, Pelizzola, Mattia, Mortellaro, Alessandra, Withers, Michael, Tanne, Antoine, Castagnoli, Paola Ricciardi, Gicquel, Brigitte, Stoker, Neil G, Butcher, Philip D, Foti, Maria and Neyrolles, Olivier (2008) Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. PLoS ONE, 3 (1). e1403. ISSN 1932-6203

Waddell, Simon J, von Kamp, Axel, Klamt, Steffen and Neyrolles, Olivier (2012) Host-pathogen interactions. In: McFadden, Johnjoe, Beste, Dany J V and Kierzek, Andrzej M (eds.) Systems Biology of Tuberculosis. Springer, pp. 107-126. ISBN 9781461449669

Waddell, Simon J. (2010) Reprogramming the Mycobacterium tuberculosis transcriptome during pathogenesis. Drug Discovery Today: Disease Mechanisms, 7 (1). e67-e73. ISSN 17406765

Wang, Yinglong, Liu, Yonglei, Zhang, Jie, Crickmore, Neil, Song, Fuping, Gao, Jiguo and Shu, Changlong (2018) Cry78Aa, a novel Bacillus thuringiensis insecticidal protein with activity against Laodelphax striatellus and Nilaparvata lugens. Journal of invertebrate pathology, 158. pp. 1-5. ISSN 1096-0805

Ward, G D, Wastson, I A, Stewart-Tull, D E S, Wardlaw, A C and Chatwin, C R (1996) Inactivation of bacteria and yeasts on agar surfaces with high power Nd: YAG laser light. Letters In Applied Microbiology, 23 (3). pp. 136-140. ISSN 0266-8254

Wildner, Leticia Muraro, Gould, Katherine A and Waddell, Simon J (2018) Transcriptional profiling mycobacterium tuberculosis from patient sputa. In: Antibiotic Resistance Protocols. Methods in Molecular BIology, 1736 . Humana Press, pp. 117-128. ISBN 9781493976362

Y

Ye, Weixing, Zhu, Lei, Liu, Yingying, Crickmore, Neil, Peng, Donghai, Ruan, Lifang and Sun, Ming (2012) Mining new crystal protein genes from Bacillus thuringiensis on the basis of mixed plasmid-enriched genome sequencing and a computational pipeline. Applied and Environmental Microbiology, 78 (14). pp. 4795-4801. ISSN 0099-2240

Z

Zhang, Fengjiao, Shu, Changlong, Crickmore, Neil, Li, Yanqiu, Song, Fuping, Liu, Chunqin, Chen, Zhibao and Zhang, Jie (2016) Use of redundant exclusion PCR to identify a novel Bacillus thuringiensis Cry8 toxin gene from pooled genomic DNA. Applied and Environmental Microbiology, 82 (13). pp. 3808-3815. ISSN 0099-2240

Zhang, Wenfei, Crickmore, Neil, George, Zenas Okon, Xie, Liu, He, Yong-Qiang, Li, Youzhi, Tang, Ji-Liang, Tian, Liang, Wang, Xi and Fang, Xuanjun (2012) Characterization of a new highly mosquitocidal isolate of Bacillus thuringiensis - an alternative to Bti? Journal of Invertebrate Pathology, 109 (2). pp. 217-222. ISSN 0022-2011