Article

Ceriani, Federico, Hendry, Aenea, Jeng, Jing‐Yi, Johnson, Stuart L, Stephani, Friederike, Olt, Jennifer, Holley, Matthew C, Mammano, Fabio, Engel, Jutta, Kros, Corné J, Simmons, Dwayne D and Marcotti, Walter (2019) Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells. EMBO Journal. e99839 1-19. ISSN 1460-2075

Corns, Laura F, Johnson, Stuart L, Roberts, Terri, Ranatunga, Kishani M, Hendry, Aenea, Ceriani, Federico, Safieddine, Saaid, Steel, Karen P, Forge, Andy, Petit, Christine, Furness, David N, Kros, Corné J and Marcotti, Walter (2018) Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. Nature communications, 9 (4015). pp. 1-15. ISSN 2041-1723

Jeong, Minjin, O'Reilly, Molly, Kirkwood, Nerissa K, Al-Aama, Jumana, Lako, Majlinda, Kros, Corné J and Armstrong, Lyle (2018) Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells. Cell Death and Disease, 9 (9922). pp. 1-13. ISSN 2041-4889

Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, O'Reilly, Molly, Derudas, Marco, Cantillon, Daire M, Goodyear, Richard J, Secker, Abigail, Baxendale, Sarah, Bull, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J and Richardson, Guy P (2017) Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death. Journal of Clinical Investigation Insight, 2 (24). ISSN 2379-3708

Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, O'Reilly, Molly, Derudas, Marco, Cantillon, Daire M, Goodyear, Richard J, Secker, Abigail, Baxendale, Sarah, Bulley, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J and Richardson, Guy P (2017) Identification of ion-channel modulators that protect against aminoglycoside-induced hair-cell death. Journal of Clinical Investigation Insight, 2 (24). ISSN 2379-3708

Corns, Laura F, Jeng, Jing-Yi, Richardson, Guy P, Kros, Corné J and Marcotti, Walter (2017) TMC2 modifies permeation properties of the mechanoelectrical transducer channel in early postnatal mouse cochlear outer hair cells. Frontiers in Molecular Neuroscience, 10. ISSN 1662-5099

Kirkwood, Nerissa K, O'Reilly, Molly, Derudas, Marco, Kenyon, Emma J, Huckvale, Rosemary, van Netten, Sietse M, Ward, Simon E, Richardson, Guy P and Kros, Corné Kros (2017) d-Tubocurarine and berbamine: alkaloids that are permeant blockers of the hair cell's mechano-electrical transducer channel and protect from aminoglycoside toxicity. Frontiers in Cellular Neuroscience, 11. ISSN 1662-5102

Marcotti, Walter, Corns, Laura F, Goodyear, Richard J, Rzadzinska, Agnieszka K, Avraham, Karen B, Steel, Karen P, Richardson, Guy P and Kros, Corné J (2016) The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI. Journal of Physiology, 594 (13). pp. 3667-3681. ISSN 0022-3751

Corns, Laura F, Johnson, Stuart L, Kros, Corne J and Marcotti, Walter (2016) Tmc1 point mutation affects Ca2+ sensitivity and block by dihydrostreptomycin of the mechanoelectrical transducer current of mouse outer hair cells. Journal of Neuroscience, 36 (2). pp. 336-349. ISSN 0270-6474

Sexton, Jane E, Desmonds, Terri, Quick, Kathryn, Taylor, Ruth, Abramowitz, Joel, Forge, Andy, Kros, Corné J, Birnbaumer, Lutz and Wood, John N (2016) The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing. Neuroscience Letters, 610. pp. 36-42. ISSN 0304-3940

Corns, Laura F, Johnson, Stuart L, Kros, Corné J and Marcotti, Walter (2014) Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells. Proceedings of the National Academy of Sciences, 111 (41). pp. 14918-14923. ISSN 1091-6490

Corns, Laura F, Johnson, Stuart L, Kros, Corné J and Marcotti, Walter (2014) Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells. Proceedings of the National Academy of Sciences, 111 (41). pp. 14918-14923. ISSN 0027-8424

Marcotti, Walter, Corns, Laura F, Desmonds, Terri, Kirkwood, Nerissa K, Richardson, Guy P and Kros, Corné J (2014) Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel. Journal of Neuroscience, 34 (16). pp. 5505-5514. ISSN 0270-6474

Johnson, Stuart L, Eckrich, Tobias, Kuhn, Stephanie, Zampini, Valeria, Franz, Christoph, Ranatunga, Kishani M, Roberts, Terri P, Masetto, Sergio, Knipper, Marlies, Kros, Corné J and Marcotti, Walter (2011) Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells. Nature Neuroscience, 14 (6). pp. 711-717. ISSN 1097-6256

Alagramam, Kumar N, Goodyear, Richard J, Geng, Ruishuang, Furness, David N, Van Aken, Alexander F J, Marcotti, Walter, Kros, Corné J and Richardson, Guy P (2011) Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells. PLoS ONE, 6 (4). e19183. ISSN 1932-6203

Roux, Isabelle, Hosie, Suzanne, Johnson, Stuart L, Bahloul, Amel, Cayet, Nadège, Nouaille, Sylvie, Kros, Corné J, Petit, Christine and Safieddine, Saaid (2009) Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses. Human Molecular Genetics, 18 (23). pp. 4615-4628. ISSN 0964-6906

Michalski, Nicolas, Michel, Vincent, Caberlotto, Elisa, Lefèvre, Gaelle M, Van Aken, Alexander F J, Tinevez, Jean-Yves, Bizard, Emilie, Houbron, Christophe, Weil, Dominique, Hardelin, Jean-Pierre, Richardson, Guy P, Kros, Corné J, Martin, Pascal and Petit, Christine (2009) Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells. Pflügers Archiv European Journal of Physiology, 459 (1). pp. 115-130. ISSN 0031-6768

van Netten, Sieste M, Meulenberg, Cécil J W, Lennan, George W T and Kros, Corné J (2009) Pairwise coupling of hair cell transducer channels links auditory sensitivity and dynamic range. Pflügers Archiv European Journal of Physiology, 458 (2). pp. 273-281. ISSN 0031-6768

Van Aken, Alexander F J, Atiba-Davies, Margaret, Marcotti, Walter, Goodyear, Richard J, Bryant, Jane E, Richardson, Guy P, Noben-Trauth, Konrad and Kros, Corné J (2008) TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. Journal of Physiology, 586 (22). pp. 5403-5418. ISSN 0022-3751

Goodyear, Richard J, Gale, Jonathan E, Ranatunga, Kishani M, Kros, Corné J and Richardson, Guy P (2008) Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible. Journal of Neuroscience, 28 (40). pp. 9939-9952. ISSN 0270-6474

Van Aken, Alexander F J, Atiba-Davies, Margaret, Marcotti, Walter, Goodyear, Richard J, Bryant, Jane E, Richardson, Guy P, Noben-Trauth, Konrad and Kros, Corné J (2008) TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. Journal of Physiology, 586 (22). pp. 5403-5418. ISSN 0022-3751

Grimm, Christian, Cuajungco, Math P, Van Aken, Alexander F J, Schnee, Michael, Jörs, Simone, Kros, Corné J, Ricci, Anthony J and Heller, Stefan (2007) A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse. Proceedings of the National Academy of Sciences, 104 (49). pp. 19583-19588. ISSN 0027-8424

Kros, Corné J (2007) How to build an inner hair cell: challenges for regeneration. Hearing Research, 227 (1-2). pp. 3-10. ISSN 0378-5955

Marcotti, Walter, Erven, Alexandra, Johnson, Stuart L, Steel, Karen P and Kros, Corné J (2006) Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea. Journal of Physiology, 574. pp. 677-698. ISSN 0022-3751

Marcotti, Walter, van Netten, Sietse M and Kros, Corné J (2005) The aminoglycoside antibiotic dihydrostreptomycin rapidly enters hair cells through the mechano-electrical transducer channels. Journal of Physiology, 567 (2). pp. 505-521. ISSN 0022-3751

Michel, Vincent, Goodyear, Richard J, Weil, Dominique, Marcotti, Walter, Perfettini, Isabelle, Wolfrum, Uwe, Kros, Corné J, Richardson, Guy P and Petit, Christine (2005) Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory hair cells. Developmental Biology, 280 (2). pp. 281-294. ISSN 0012-1606

Johnson, Stuart L, Marcotti, Walter and Kros, Corné J (2005) Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells. Journal of Physiology, 563 (1). pp. 177-191. ISSN 0022-3751

Goodyear, Richard J, Marcotti, Walter, Kros, Corné J and Richardson, Guy P (2005) Development and properties of stereociliary link types in hair cells of the mouse cochlea. Journal of Comparative Neurology, 485 (1). 75 - 85. ISSN 0021-9967

Marcotti, Walter, Johnson, Stuart L and Kros, Corné J (2004) Effects of intracellular stores and extracellular Ca2+ on Ca2+-activated K+ currents in mature mouse inner hair cells. Journal of Physiology, 557. pp. 613-633. ISSN 0022-3751

Marcotti, Walter, Johnson, Stuart L and Kros, Corné J (2004) A transiently expressed SK current sustains and modulates action potential activity in immature mouse inner hair cells. Journal of Physiology, 560. pp. 691-708. ISSN 0022-3571

van Netten, Sietse M, Dinklo, Theo, Marcotti, Walter and Kros, Corné J (2003) Channel gating forces govern accuracy of mechano-electrical transduction in hair cells. Proceedings of the National Academy of Sciences, 100 (26). pp. 15510-15515. ISSN 0027-8424

Goodyear, R J, Legan, P K, Wright, M B, Marcotti, W, Oganesian, A, Coats, S A, Booth, C J, Kros, C J, Seifert, R A, Bowen-Pope, D F and Richardson, G P (2003) A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. Journal of Neuroscience, 23 (27). pp. 9208-9219. ISSN 0270-6474

Gorelik, Julia, Shevchuk, Andrew I, Frolenkov, Gregory I, Diakonov, Ivan A, Lab, Max J, Kros, Corné J, Richardson, Guy P, Vodyanoy, Igor, Edwards, Christopher R W, Klenerman, David and Korchev, Yuri E (2003) Dynamic assembly of surface structure in living cells. Proceedings of the National Academy of Sciences, 100 (10). ISSN 0027-8424

Marcotti, Walter, Johnson, Stuart L, Holley, Matthew C and Kros, Corné J (2003) Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells. Journal of Physiology, 548 (2). pp. 383-400. ISSN 0022-3751

Marcotti, Walter, Johnson, Stuart L, Rüsch, Alfons and Kros, Corné J (2003) Sodium and calcium currents shape action potentials in immature mouse inner hair cells. Journal of Physiology, 552. pp. 743-761. ISSN 0022-3751

Kros, C J, Marcotti, W, van Netten, S M, Self, T J, Libby, R T, Brown, S D M, Richardson, G P and Steel, K P (2002) Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations. Nature Neuroscience, 5 (1). pp. 41-47. ISSN 1097-6256

Gale, J E, Marcotti, W, Kennedy, H J, Kros, C J and Richardson, G P (2001) FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel. Journal of Neuroscience, 21 (18). pp. 7013-7025. ISSN 0270-6474

Richardson, G P, Forge, A, Kros, C J, Marcotti, W, Becker, D, Williams, D S, Thorpe, J, Fleming, J, Brown, S D and Steel, K P (1999) A missense mutation in myosin VIIA prevents aminoglycoside accumulation in cochlear hair cells. Annals of the New York Academy of Sciences, 884. pp. 110-124.

Marcotti, Walter and Kros, Corné J (1999) Developmental expression of the potassium current kn contributes to maturation of mouse outer hair cells. Journal of Physiology, 520 (3). 653 - 660. ISSN 0022-3751

Kros, Corné J, Ruppersberg, J Peter and Rüsch, Alfons (1998) Expression of a potassium current in inner hair cells during development of hearing in mice. Nature, 394 (6690). 281 - 284. ISSN 00280836

Richardson, G P, Forge, A, Kros, C J, Fleming, J, Brown, S D M and Steel, K P (1997) Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells. Journal of Neuroscience, 17 (24). pp. 9506-9519. ISSN 02706474

Book Section

Goodyear, Richard J, Kros, Corné J and Richardson, Guy P (2006) The development of hair cells in the inner ear. In: Eatock, Ruth Anne, Fay, Richard R and Popper, Arthur N (eds.) Vertebrate Hair Cells. Springer Verlag. ISBN 978-0-387-95202-4