Items for Gosling, Martin

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Miller, Andrew T, Dahlberg, Carol, Sandberg, Mark L, Wen, Ben G, Beisner, Daniel R, Hoerter, John A H, Parker, Albert, Schmedt, Christian, Stinson, Monique, Avis, Jacqueline, Cienfuegos, Cynthia, McPate, Mark, Tranter, Pamela, Gosling, Martin, Groot-Kormelink, Paul J, Dawson, Janet, Pan, Shifeng, Tian, Shin-Shay, Seidel, H Martin and Cooke, Michael P (2015) Inhibition of the inositol kinase Itpkb augments calcium signaling in lymphocytes and reveals a novel strategy to treat autoimmune disease. PLoS ONE, 10 (6). e0131071. ISSN 1932-6203

Coote, K J, Paisley, D, Czarnecki, S, Tweed, M, Watson, H, Young, A, Sugar, R, Vyas, M, Smith, N J, Baettig, U, Groot-Kormelink, P J, Gosling, M, Lock, R, Ethell, B, Williams, G, Schumacher, A, Harris, J, Abraham, W M, Sabater, J, Poll, C T, Faller, T, Collingwood, S P and Danahay, H (2015) NVP-QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia. British Journal of Pharmacology, 172 (11). pp. 2814-2826. ISSN 0007-1188

Bill, Anke, Popa, M Oana, Van Diepen, Michiel T, Gutierrez, Abraham, Lilley, Sarah, Velkova, Maria, Acheson, Kathryn, Choudhury, Hedaythul, Renaud, Nicole A, Auld, Douglas S, Gosling, Martin, Groot-Kormelink, Paul J and Gaither, L Alex (2015) Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation. Journal of Biological Chemistry, 290 (2). pp. 889-903. ISSN 0021-9258

Arnold, Nicola, Beattie, David, Bradley, Michelle, Brearley, Andrew, Brown, Lyndon, Charlton, Steven J, Fairhurst, Robin A, Farr, David, Fozard, John, Fullerton, Joe, Gosling, Martin, Hatto, Julia, Janus, Diana, Jones, Darryl, Jordan, Lynne, Lewis, Christine, Maas, Janet, McCarthy, Clive, Mercer, Mark, Oakman, Helen, Press, Neil, Profit, Rachel, Schuerch, Friedrich, Sykes, David, Taylor, Roger J, Trifilieff, Alexandre and Tuffnell, Andrew (2014) The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1- hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist. Bioorganic and Medicinal Chemistry Letters, 24 (17). pp. 4341-4347. ISSN 0960-894X

McPate, Mark, Bhalay, Gurdip, Beckett, Martin, Fairbrother, Sian, Gosling, Martin, Groot-Kormelink, Paul J, Lane, Rebecca, Kent, Toby, Van Diepen, Michiel T, Tranter, Pamela and Verkuyl, J Martin (2014) The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7. Assay and Drug Development Technologies, 12 (5). pp. 282-292. ISSN 1540-658X

Bill, Anke, Rosethorne, Elizabeth M, Kent, Toby C, Fawcett, Lindsay, Burchell, Lynn, Van Diepen, Michiel T, Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P, Renaud, Nicole A, Charlton, Steven J, Gosling, Martin, Gaither, L Alex and Groot-Kormelink, Paul J (2014) High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor. PLoS ONE, 9 (6). e97973. ISSN 1932-6203

Britschgi, Adrian, Bill, Anke, Brinkhaus, Heike, Rothwell, Christopher, Clay, Ieuan, Duss, Stephan, Rebhan, Michael, Raman, Pichai, Guy, Chantale T, Wetzel, Kristie, George, Elizabeth, Popa, M Oana, Lilley, Sarah, Choudhury, Hedaythul, Gosling, Martin, Wang, Louis, Fitzgerald, Stephanie, Borawski, Jason, Baffoe, Jonathan, Labow, Mark, Gaither, L Alex and Bentires-Alj, Mohamed (2013) Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (11). E1026-E1034. ISSN 1091-6490

Groot-Kormelink, Paul J, Fawcett, Lindsay, Wright, Paul D, Gosling, Martin and Kent, Toby C (2012) Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates. BMC Immunology, 13 (57). ISSN 1471-2172

Beattie, David, Bradley, Michelle, Brearley, Andrew, Charlton, Steven J, Cuenoud, Bernard M, Fairhurst, Robin A, Gedeck, Peter, Gosling, Martin, Janus, Diana, Jones, Darryl, Lewis, Christine, McCarthy, Clive, Oakman, Helen, Stringer, Rowan, Taylor, Roger J and Tuffnell, Andrew (2010) A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators. Bioorganic and Medicinal Chemistry Letters, 20 (17). pp. 5302-5307. ISSN 0960-894X

Finney-Hayward, Tricia K, Popa, Mariana Oana, Bahra, Parmjit, Li, Su, Poll, Christopher T, Gosling, Martin, Nicholson, Andrew G, Russell, Richard E K, Kon, Onn Min, Jarai, Gabor, Westwick, John, Barnes, Peter J and Donnelly, Louise E (2010) Expression of transient receptor potential C6 channels in human lung macrophages. American Journal of Respiratory Cell and Molecular Biology, 43 (3). pp. 296-304. ISSN 1044-1549

Golledge, J, Gosling, M, Turner, R J, Standfield, N J and Powell, J T (2010) Arterial flow induces changes in saphenous vein endotheliumproteins transduced by cation channels. European Journal of Vascular and Endovascular Surgery, 19 (5). pp. 545-550. ISSN 1078-5884

Paisley, Derek, Gosling, Martin and Danahay, Henry (2010) Regulation of airway mucosal hydration. Expert Review of Clinical Pharmacology, 3 (3). pp. 361-369. ISSN 1751-2433

Coote, K, Atherton-Watson, H C, Sugar, R, Young, A, MacKenzie-Beevor, A, Gosling, M, Bhalay, G, Bloomfield, G, Dunstan, A, Bridges, R J, Sabater, J R, Abraham, W M, Tully, D, Pacoma, R, Schumacher, A, Harris, J and Danahay, H (2009) Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. Journal of Pharmacology and Experimental Therapeutics, 329 (2). pp. 764-774. ISSN 0022-3565

Coote, K J, Atherton, H, Young, A, Sugar, R, Burrows, R, Smith, N J, Schlaeppi, J-M, Groot-Kormelink, P J, Gosling, M and Danahay, H (2008) The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways. British Journal of Pharmacology, 155 (7). pp. 1025-1033. ISSN 0007-1188

Stansfeld, Phillip J, Grottesi, Alessandro, Sands, Zara A, Sansom, Mark S P, Gedeck, Peter, Gosling, Martin, Cox, Brian, Stanfield, Peter R, Mitcheson, John S and Sutcliffe, Michael J (2008) Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations. Biochemistry, 47 (28). pp. 7414-7422. ISSN 0006-2960

Stansfeld, Phillip J, Gedeck, Peter, Gosling, Martin, Cox, Brian, Mitcheson, John S and Sutcliffe, Michael J (2007) Drug block of the hERG potassium channel: insight from modeling. Proteins: Structure, Function, and Bioinformatics, 68 (2). pp. 568-580. ISSN 0887-3585

Wales, Lucy, Gosling, Martin, Taylor, Graham W, Davies, Alun H and Powell, Janet T (2006) The potassium channel opener levcromakalim causes expansive remodelling of experimental vein grafts. Journal of Vascular Surgery, 44 (1). pp. 159-165. ISSN 0741-5214

Li, Su, Gosling, Martin and Poll, Chris (2005) Determining the functional role of TRPC channels in primary cells. Pflugers Archiv European Journal of Physiology, 451 (1). pp. 43-52. ISSN 0031-6768

Gosling, Martin, Poll, Chris and Li, Su (2005) TRP channels in airway smooth muscle as therapeutic targets. Naunyn-Schmiedeberg's Archives of Pharmacology, 371 (4). pp. 277-284. ISSN 0028-1298

Li, Su, Gosling, Martin, Poll, Chris T, Westwick, John and Cox, Brian (2005) Therapeutic scope of modulation of non-voltage-gated cation channels. Drug Discovery Today, 10 (2). pp. 129-137. ISSN 1359-6446

Sultan, Sabena, Gosling, Martin, Abu-Hayyeh, Shadi, Carey, Nessa and Powell, Janet T (2004) Flow-dependent increase of ICAM-1 on saphenous vein endothelium is sensitive to apamin. American Journal of Physiology - Heart and Circulatory Physiology, 287 (1 56-1). H22-H28. ISSN 0363-6135

Estacion, Mark, Li, Su, Sinkins, William G, Gosling, Martin, Bahra, Parmjit, Poll, Chris, Westwick, John and Schilling, William P (2004) Activation of human TRPC6 channels by receptor stimulation. Journal of Biological Chemistry, 279 (21). pp. 22047-22056. ISSN 0021-9258

Sultan, Sabena, Gosling, Martin, Nagase, Hideaki and Powell, Janet T (2004) Shear stress-induced shedding of soluble intercellular adhesion molecule-1 from saphenous vein endothelium. FEBS Letters, 564 (1-2). pp. 161-165. ISSN 0014-5793

McGregor, Emma, Kempster, Lee, Wait, Robin, Gosling, Martin, Dunn, Michael J and Powell, Janet T (2004) F-actin capping (CapZ) and other contractile saphenous vein smooth muscle proteins are altered by hemodynamic stress: a proteomic approach. Molecular and Cellular Proteomics, 3 (2). pp. 115-124. ISSN 1535-9476

Norman, Paul, Moss, Ian, Sian, Minder, Gosling, Martin and Powell, Janet (2002) Maternal and postnatal vitamin D ingestion influences rat aortic structure, function and elastin content. Cardiovascular Research, 55 (2). pp. 369-374. ISSN 0008-6363

McGregor, Emma, Gosling, Martin, Beattie, David K, Ribbons, Duncan M P, Davies, Alun H and Powell, Janet T (2002) Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways. Cardiovascular Research, 53 (1). pp. 219-226. ISSN 0008-6363

Scoumanne, Ariane, Kalamati, Tahereh, Moss, Jill, Powell, Janet T, Gosling, Martin and Carey, Nessa (2002) Generation and characterisation of human saphenous vein endothelial cell lines. Atherosclerosis, 160 (1). pp. 59-67. ISSN 0021-9150

McGregor, Emma, Kempster, Lee, Wait, Robin, Welson, Sandy Y, Gosling, Martin, Dunn, Michael J and Powell, Janet T (2001) Identification and mapping of human saphenous vein medial smooth muscle proteins by two-dimensional polyacrylamide gel electrophoresis. Molecular and Cellular Proteomics, 1 (11). pp. 1405-1414. ISSN 1615-9853

Golledge, J, Gosling, M, Turner, R J, Standfield, N J and Powell, J T (2000) Arterial flow induces changes in saphenous vein endothelium proteins transduced by cation channels. European Journal of Vascular and Endovascular Surgery, 19 (5). pp. 545-550. ISSN 1078-5884

Turner, Robert J, Gosling, Martin, Powell, Janet T and Golledge, Jonathan (1999) Rapid changes in the coagulant proteins on saphenous vein endothelium in response to arterial flow. International Journal of Angiology, 50 (9). pp. 693-701. ISSN 0003-3197

Gosling, Martin, Golledge, Jonathan, Turner, Robert J and Powell, Janet T (1999) Arterial flow conditions downregulate thrombomodulin on saphenous vein endothelium. Circulation, 99 (8). pp. 1047-1053. ISSN 0009-7322

Powell, Janet T and Gosling, Martin (1998) Molecular and cellular changes in vein grafts: influence of pulsatile stretch. Current Opinion in Cardiology, 13 (6). pp. 453-458. ISSN 0268-4705

Gosling, Martin, Harley, Suzanne L, Turner, Robert J, Carey, Nessa and Powell, Janet T (1998) Human saphenous vein endothelial cells express a tetrodotoxin- resistant, voltage-gated sodium current. Journal of Biological Chemistry, 273 (33). pp. 21084-21090. ISSN 0021-9258

Beattie, D K, Gosling, M, Davies, A H and Powell, J T (1998) The effects of potassium channel openers on saphenous vein exposed to arterial flow. European Journal of Vascular and Endovascular Surgery, 15 (3). pp. 244-249. ISSN 1078-5884

Conference or Workshop Item

Danahay, H, Coote, K, Paisley, D, Czarnecki, S, Atherton, H, Young, A, Gosling, M, Abraham, W, Sabater, J, Lock, R, Smith, N, Stanley, E, Butler, R, Bloomfield, G, Baettig, U, Cox, B and Collingwood, S P (2010) Novel dimeric amiloride derivatives: airway efficacy & reduced renal-based side effects. In: The 24th Annual North American Cystic Fibrosis Conference, October 21-23, 2010, Baltimore, Maryland, USA.

Edited Book

Cox, Brian and Gosling, Martin, eds. (2014) Ion channel drug discovery. RSC drug discovery . Royal Society of Chemistry. ISBN 9781849731867

This list was generated on Thu Jun 8 00:20:21 2023 BST.